CMCR Grants Program

The Center for Medicinal Cannabis Research (CMCR) seeks to fund primary and pilot cannabis-related studies that further enhance the understanding of the efficacy and adverse effects of cannabis and cannabinoids as pharmacological agents for the treatment of medical and psychiatric disorders, and their potential public health impacts. Primary project awards are up to $825,000 in total costs ($275,000 per year) for up to three years. Pilot awards are up to $300,000 for two years ($150,000 per year).

Link to the 2026 CMCR Grants Program call for Proposals

Studies Funded to Date: CMCR Grants Program

CMCR Studies

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STUDY TITLE PRINCIPAL INVESTIGATOR AFFILIATION FUNDING SOURCE STATUS
Analgesic, appetite-stimulating, and subjective effects of CBG and THC Cooper, Ziva, PhD UC Los Angeles CMCR Active (Enrolling)
Antinociceptive effects of phytocannabinoids in a mouse model of SCD Piomelli, Daniele, PhD UC Irvine CMCR Active
Assessing the Impact of Real-World Cannabis Products on Driving and Cognition Marcotte, Thomas, PhD UC San Diego State of California Active (Enrolling)
Cannabidiol use during pregnancy: Safety and risk for the developing fetus Thomas, Jennifer, PhD San Diego State University CMCR Active
Cannabis and Pathogenic Mechanisms influencing Blood Brain Barrier Function in HIV Iudicello, Jennifer, PhD UC San Diego NIH Active (Enrolling)
Cannabis effects on antiretroviral therapy pharmacokinetics and neurotoxicity Letendre, Scott, MD UC San Diego NIH Active
Cannabis, inflammation, and the brain in persons with HIV Iudicello, Jennifer, PhD UC San Diego NIH Active (Enrolling)
Contribution of genetic factors to individual differences in anxiety Inman, Jamie, PhD Lawrence Berkeley National Laboratory CMCR Active
Effects of CBD versus Placebo as an Adjunct to Treatment in Early Psychosis Cadenhead, Kristin, MD UC San Diego CMCR/KEF Active (Enrolling)
Effects of CBD and THC on the microbiome, ECS and neuroinflammation in HIV Ellis, Ron, MD, PhD UC San Diego NIH Active (Enrolling)
Evaluating the efficacy of cannabidiol for reducing cigarette use London, Edythe, PhD UC Los Angeles CMCR Active
Impact of perioperative CBD exposure in orthopaedic implant infections Bernthal, Nicholas, MD UC Los Angeles CMCR Active
Impact of Cannabis Exposure on Gut Barrier Function in Health and Disease DiPatrizio, Nicholas, PhD UC Riverside CMCR Active
Myrcene modulates on CB1 receptor function via enhancement of endocannabinoids Cahill, Catherine, PhD UC Los Angeles CMCR Active
Sex differences in CBD’s effects on blood pressure Guo, Zhi-Ling, MD, PhD UC Irvine CMCR Active
Terpenes as novel analgesics - preclinical study Cahill, Catherine, PhD UC Los Angeles CMCR Active
Brain mechanisms supporting cannabis-induced chronic low back pain relief Zeidan, Fadel, PhD UC San Diego CMCR Active
Effects of THC on Glucose Metabolism and Endothelial Function in Type 2 Diabetes Pettus, Jeremy, MD UC San Diego CMCR Active
Therapeutic Response of Cannabidiol in Rheumatoid Arthritis Ranganath, Veena, MD UC Los Angeles CMCR COMPLETED
Translational studies of cannabis administration, cognition, and the endocannabinoid system in HIV Minassian, Arpi, PhD UC San Diego NIH Active
Cannabis for Treatment of HIV-Related Peripheral Neuropathy Abrams, Donald, MD UC San Francisco CMCR COMPLETED
Vaporization as a "Smokeless" Cannabis Delivery System Abrams, Donald, MD UC San Francisco CMCR COMPLETED
Short-Term Effects of Cannabis Therapy on Spasticity in MS Corey-Bloom, Jody, MD, PhD UC San Diego CMCR COMPLETED
Cannabidiol as a Strategy to Treat Alcohol Dependence de Guglielmo, Giordano, PhD UC San Diego CMCR COMPLETED
Sleep and Medicinal Cannabis Drummond, Sean, PhD UC San Diego CMCR COMPLETED
Placebo-controlled, double-blind trial of medicinal cannabis in painful HIV neuropathy Ellis, Ron, MD, PhD UC San Diego CMCR COMPLETED
CBD in Regulating Meal Time Anxiety in Anorexia Nervosa Frank, Guido, MD UC San Diego CMCR COMPLETED
Effect of Cannabis and Endocannabinoids on HIV Neuropathic Pain Henry, Brook, PhD & Ellis, Ron, MD UC San Diego CMCR COMPLETED
A Randomized, Controlled Trial of Cannabis in Healthy Volunteers: Evaluating Simulated Driving, Field Performance Tests and Cannabinoid Levels Marcotte, Thomas, PhD UC San Diego CMCR COMPLETED
Dronabinol and Vaporized Cannabis in Neuropathic Low Back Pain Marcotte, Thomas, PhD UC San Diego CMCR COMPLETED
Impact of Repeated Cannabis Treatments on Driving Abilities Marcotte, Thomas, PhD UC San Diego CMCR COMPLETED
Mechanisms of Cannabinoid Analgesia Meng, Ian, PhD UC Davis CMCR COMPLETED
A Pilot Study of the Efficacy of Cannabidiol (CBD) on Tremor Severity in Essential Tremor (ET) Nahab, Fatta, MD UC San Diego CMCR COMPLETED
Effects of CBD on Blood Pressure and Substrate Metabolism during Metabolic Syndrome Ortiz, Rudy, PhD UC Merced CMCR COMPLETED
Cannabis Use and the ECS in Bipolar Disorder Perry, William, PhD & Young, Jared, PhD UC San Diego CMCR COMPLETED
Effects of Cannabis Therapy on Endogenous Cannabinoids Piomelli, Daniele, PhD UC Irvine CMCR COMPLETED
Effects of Medicinal Cannabis on CD4 Immunity in AIDS Schrier, Rachel, PhD UC San Diego CMCR COMPLETED
Efficacy of Inhaled Cannabis versus Placebo for the Acute Treatment of Migraine Schuster, Nathaniel, MD UC San Diego Migraine Research Foundation COMPLETED
Therapeutic efficacy of cannabis and cannabinoids in prescription opioid abuse and addiction Taffe, Michael, PhD UC San Diego CMCR COMPLETED
Engaging the Endocannabinoid System with Cannabidiol to Reduce Anxiety Reactivity Taylor, Charles, PhD UC San Diego CMCR COMPLETED
The Effects of CBD on Symptoms of Severe Autism Trauner, Doris, MD UC San Diego CMCR COMPLETED
Analgesic Efficacy of Smoked Cannabis Wallace, Mark, MD UC San Diego CMCR COMPLETED
Efficacy of Inhaled Cannabis in Diabetic Peripheral Neuropathy Wallace, Mark, MD UC San Diego CMCR COMPLETED
The Analgesic Effect of Vaporized Cannabis on Neuropathic Pain in Spinal Cord Injury Wilsey, Barth, MD UC Davis CMCR COMPLETED
A Double Blind, Active Placebo Controlled Crossover Trial of the Antinociceptive Effects of Smoked Marijuana on Subjects with Neuropathic Pain; Correlation with Changes in Mood, Cognition, and Psychomotor Performance Wilsey, Barth, MD UC Davis CMCR COMPLETED