Cannabis, inflammation, and the brain in persons with HIV
PI: Jennifer Iudicello, PhD
This study will examine the effects of chronic cannabis use and the role of the endocannabinoid system on persistent inflammation in people with HIV.
Current Studies
Effect of Cannabis and Endocannabinoids on HIV Neuropathic Pain
PI: Brook Henry, Ph.D. & Ron Ellis, M.D., Ph.D.
This study will address these three fundamental gaps in our knowledge by: 1) examining the acute effects of various CBD/THC products on HIV-NP, 2) utilizing a mHealth text messaging protocol (Individual Monitoring of Pain and Cannabis Taken or IMPACT) to monitor daily real-world cannabis use and changes in pain; 3) studying the relationship between cannabinoids, EC biomarkers, and chronic neuropathic pain.
Effects of Cannabidiol (CBD) versus Placebo as an Adjunct to Treatment in Early Psychosis
PI: Kristin Cadenhead, MD
This clinical trial will explore the effectiveness of cannabidiol (CBD), in reducing symptoms and improving cognition in early psychosis. Additionally, this trial will examine the effect of CBD on the biological response to stress, and the effect of CBD on eating behavior induced by antipsychotic medication.
Effects of cannabidiol and tetrahydrocannabinol on the microbiome, endocannabinoids and neuroinflammation in HIV
PI: Ron Ellis, MD, PhD
This study will examine the microbiome and endocannabinoid system in people with HIV and how they relate to neuroinflamation and the blood-brain-barrier.
Effects of CBD on blood pressure and substrate metabolism during metabolic syndrome
PI: Rudy Ortiz, PhD
This is a pre-clinical study regarding the effects of CBD on blood pressure and factors related to metabolic syndrome
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